Mosby's 2014 Nursing Drug Reference

BOOK: Mosby's 2014 Nursing Drug Reference
6.09Mb size Format: txt, pdf, ePub


Linda Skidmore-Roth, RN, MSN, NP


Littleton, Colorado

, Nursing Faculty

New Mexico State University

Las Cruces, New Mexico

El Paso Community College

El Paso, Texas

General Index































How to Use

3251 Riverport Lane         

St. Louis, Missouri 63043


ISBN: 978-0-323-17007-9
ISSN: 1044-8470

Copyright © 2014, 2013 by Mosby, an imprint of Elsevier Inc.

Copyright © 2012, 2011 by Mosby, Inc., an affiliate of Elsevier Inc.

All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency can be found at our website:

This book and the individual contributions contained in it are protected under copyright by the publisher (other than as may be noted herein).


Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.

With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.

To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

ISBN: 978-0-323-17007-9

Director, eContent Solutions:
Robin Carter

Content Development Specialist:
Shephali Graf

Content Coordinator:
Samantha Taylor

Publishing Services Manager:
Pat Joiner

Senior Project Manager:
Joy Moore

Design Direction:
Jessica Williams


Timothy Loren Brenner, PharmD, BCOP

Clinical Pharmacy Specialist
UPMC Cancer Centers
Pittsburgh, Pennsylvania

Claudia Chiesa, PhD, RPh

Staff Pharmacist
Catalina Pharmacy Management Services
Tucson, Arizona

David S. Chun, PharmD, BCPS

Richmond Heights, Missouri

Shelley Fess, MS, RN, AOCN, CRNI, CNE

Nursing Learning Center Coordinator
Monroe Community College
Rochester, New York

Kimberly Gamache, RN, BSN

Clinical Coordinator Heart and Vascular Surgery
Baystate Medical Center
Enfield, Connecticut

Amanda Gross, RPh

Clinical Pharmacist
University of Colorado Hospital
Aurora, Colorado

Christopher T. Owens, PharmD, BCPS

Associate Professor and Chair
Department of Pharmacy Practice
Idaho State University College of Pharmacy
Pocatello, Idaho

Adam B. Pesaturo, PharmD, BCPS

Critical Care Pharmacist
Department of Pharmacy Services
Baystate Medical Center
Springfield, Massachusetts

Sarah R. Pool, RN, MS

Nursing Education Specialist Cardiac Surgery
Mayo Clinic
Rochester, Minnesota

Randolph E. Regal, PharmD, RPh, BS

Clinical Associate Professor
Adult Internal Medicine
University of Michigan Hospitals and College of Pharmacy
Ann Arbor, Michigan

Stephen M. Setter, PharmD, CDE, CGP, DVM

Assistant Professor of Pharmacotherapy
Washington State University
Spokane, Washington

Travis E. Sonnet, PharmD, FASCP

Clinical Assistant Professor
Washington State University
Spokane, Washington

Shamim Tejani, PharmD

Clinical Pharmacist
Adelante Healthcare
Phoenix, Arizona

Kristin A. Tuiskula, PharmD, RPh

Assistant Professor
Massachusetts College of Pharmacy and Health Sciences
Worcester, Massachusetts


Increasingly, patients are relying on nurses to know every detail of health care. More important, nurses are expected to have these answers, especially when it comes to medication. Let
Mosby’s 2014 Nursing Drug Reference
be your answer. Our indispensable, yet compact, resource contains hundreds of monographs with several easy-to-use features.


This edition features:

  • A beautiful, full-color design to spotlight critical and safety-related information
  • More than 20 recent FDA-approved drugs located throughout the book and in
    Appendix A
    (see Contents for a complete list). Included are monographs for:
    • ivacaftor (Kalydeco)—for cystic fibrosis
    • lucinactant (Surfaxin)—for newborn respiratory distress
    • pertuzumab (Perjeta)—for breast cancer
  • Newly added complete monographs for select ophthalmic, otic, nasal, and topical products
  • A new ebook with easy-to-use navigation for quick access to drug monographs of your choice

This edition features more than 2000 new drug facts, including:

  • New drugs and dosage information
  • Newly researched side effects and adverse reactions
  • New and revised Black Box Warnings
  • The latest precautions, interactions, and contraindications
  • IV therapy updates
  • Revised nursing considerations
  • Updated patient/family teaching guidelines

This reference is organized into three main sections:

  • Drug categories
  • Individual drug monographs (in alphabetical order by generic name)
  • Appendixes (identified by the wide, blue thumb tabs on the edge)

The guiding principle behind this book is to provide fast, easy access to drug information and nursing considerations. Every detail—the paper, typeface, cover, binding, use of color, and appendixes—has been carefully chosen with the user in mind.


This book contains monographs for more than 1300 generic and 4500 trade medications. Common trade names are given for all drugs regularly used in the United States and Canada, with drugs available only in Canada identified by a maple leaf

The following information is provided, whenever possible, for safe, effective administration of each drug:

High-alert status:
Identifies high-alert drugs with a label and icon. Visit the Institute for Safe Medication Practices (ISMP) at
for a list of medications and drug classes with the greatest potential for patient harm if they are used in error

Tall man lettering:
Uses the capitalization of distinguishing letters to avoid medication errors and is required by the FDA for drug manufacturers.

Helps the nurse master complex generic names.

Identifies prescription or over-the-counter drugs.

Functional and chemical classifications:
Allow the nurse to see similarities and dissimilarities among drugs in the same functional but different chemical classes.

Do not confuse:
Present drug names that might easily be confused within each appropriate monograph.

Describes pharmacologic properties concisely.

List the conditions the drug is used to treat.

Unlabeled uses:
Describe drug uses that may be encountered in practice but are not yet FDA approved.

Dosages and routes:
List all available and approved dosages and routes for adult, pediatric, and geriatric patients.

Available forms:
Include tablets, capsules, extended-release, injectables (IV, IM, SUBCUT), solutions, creams, ointments, lotions, gels, shampoos, elixirs, suspensions, suppositories, sprays, aerosols, and lozenges.

Side effects:
Groups these reactions by body system, with common side effects
and life-threatening reactions (those that are potentially fatal and/or permanently disabling) in
bold, red type
for emphasis.

List conditions under which the drug absolutely should not be given, including FDA pregnancy safety categories D or X.

List conditions that require special consideration when the drug is prescribed, including FDA pregnancy safety categories A, B, or C.

Black Box Warnings:
Identify FDA warnings that highlight serious and life-threatening adverse effects.

Outlines metabolism, distribution, and elimination.

Include confirmed drug interactions, followed by the drug or nutrient causing that interaction, when applicable.

Highlight potential interactions between herbal products and prescription or OTC drugs.

Identifies many common drug interactions with foods.

Drug/lab test:
Identifies how the drug may affect lab test results.

Nursing considerations:
Identify key nursing considerations for each step of the nursing process: Assess, Administer, Perform/Provide, Evaluate, and Teach Patient/Family. Instructions for giving drugs by various routes (e.g., PO, IM, IV) are included, with route subheadings in bold.

List syringe,
-site, and additive compatibilities and incompatibilities. If no compatibilities are listed for a drug, the necessary compatibility testing has not been done and that compatibility information is unknown. To ensure safety, assume that the drug may not be mixed with other drugs unless specifically stated.

“Nursing Alert” icon
: Highlights a critical consideration.

Treatment of overdose:
Provides drugs and treatment for overdoses where appropriate.


Selected new drugs:
Includes comprehensive information on 23 key drugs approved by the FDA during the past 12 months.

Ophthalmic, otic, nasal, and topical products:
Provides essential information for more than 80 ophthalmic, otic, nasal, and topical products commonly used today, grouped by chemical drug class.

Vaccines and toxoids:
Features an easy-to-use table with generic and trade names, uses, dosages and routes, and contraindications for 43 key vaccines and toxoids.

I am indebted to the nursing and pharmacology consultants who reviewed the manuscript and thank them for their criticism and encouragement. I would also like to thank Robin Carter and Shephali Graf, my editors, whose active encouragement and enthusiasm have made this book better than it might otherwise have been. I am likewise grateful to Joy Moore and Graphic World Inc. for the coordination of the production process and assistance with the development of the new edition.

Linda Skidmore-Roth




FDA pregnancy categories


No risk demonstrated to the fetus in any trimester
No adverse effects in animals; no human studies available
Only given after risks to the fetus are considered; animal studies have shown adverse reactions; no human studies available
Definite fetal risks, may be given in spite of risks if needed in life-threatening conditions
Absolute fetal abnormalities; not to be used at any time during pregnancy

= Unknown fetal risk (used in this text but not an official FDA pregnancy category)

BOOK: Mosby's 2014 Nursing Drug Reference
6.09Mb size Format: txt, pdf, ePub

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