Mosby's 2014 Nursing Drug Reference (443 page)
Read Mosby's 2014 Nursing Drug Reference Online
Authors: Linda Skidmore-Roth
ANTIFUNGALS
butoconazole (
OTC
)
(byoo-toh-kone′ah-zole)
Gynazol-1
miconazole (
OTC
)
(mye-kon′a-zole)
Monistat, Monistat 3, Monistat 7, Monistat Dual Pak
terconazole (
OTC
)
(ter-kone′ah-zole)
Terazol 7, Terazol 3, Zazole
tioconazole (
OTC
)
(tye-oh-kone′ah-zole)
Gyne-Trosyd
, Vagistat-1
Interferes with fungal DNA replication; binds sterols in fungal cell membranes, which increases permeability, leaking of nutrients
Vaginal, vulval, vulvovaginal candidiasis (moniliasis)
Hypersensitivity
Precautions:
Pregnancy, breastfeeding, children <2 yr
Calculator
• Adult:
VAG
5 g (1 applicator) at bedtime × 3-6 days
• Adult:
200 mg supp at bedtime × 3 days or 100 mg supp × 1 wk
• Adult:
VAG 5 g (1 applicator) at bedtime
• Adult:
1 applicator at bedtime
Topical route
•
One full applicator every night high into the vagina
•
Store at room temperature in dry place
GU:
Vulvovaginal burning, itching, pelvic cramps
INTEG:
Rash, urticaria, stinging, burning
MISC:
Headache, body pain
•
For allergic reaction: burning, stinging, itching, discharge, soreness
•
Therapeutic outcome: decrease in itching or white discharge (vaginal)
•
About asepsis (hand washing) before, after each application
•
To apply with applicator only; to avoid use of any other vaginal product unless directed by prescriber; sanitary napkin may prevent soiling of undergarments
•
To abstain from sexual intercourse until treatment is completed; reinfection and irritation may occur
•
To notify prescriber if symptoms persist
Canada only Side effects:
italics
= common;
bold
= life-threatening 
Nurse Alert
ANTIINFECTIVES
ciprofloxacin (Rx)
Cetraxel
Inhibits protein synthesis in susceptible microorganisms
Ear infection (external), short-term use
Hypersensitivity, perforated eardrum
Precautions:
Pregnancy (C)
•
After removing impacted cerumen by irrigation
•
After cleaning stopper with alcohol
•
After restraining child if necessary
•
After warming sol to body temp
EENT:
Itching, irritation in ear
INTEG:
Rash, urticaria
•
For redness, swelling, fever, pain in ear, which indicates superinfection
•
Therapeutic response: decreased ear pain
•
The correct method of instillation using aseptic technique, including not touching dropper to ear
•
That dizziness may occur after instillation
Canada only Side effects:
italics
= common;
bold
= life-threatening Nurse Alert
Vaccines and toxoids
Canada only Side effects:
italics
= common;
bold
= life-threatening Nurse Alert
