DESCRIPTION
- General:
- Normal venous sinusoids of the distal rectum and proximal anal canal
- Normal vascular cushions of anal canal that contribute to anal continence
- Arteriovenous shunt system exists at the level of the internal hemorrhoids that accounts for the bright red blood per rectum
- When the hemorrhoids become symptomatic, hemorrhoid disease develops.
- Do not cause pain unless thrombosed or strangulated
- Discrete masses of thick submucosa contain:
- Blood vessels
- Smooth muscle
- Elastic and connective tissue
- Sliding down of part of anal canal lining
- External hemorrhoids:
- Vessels situated below dentate line
- Covered by skin/anoderm
- Drain to internal iliac veins
- Internal hemorrhoids:
- Submucosal vessels above dentate lines
- Drain to portal system
- Usually at left lateral, right posterolateral, and right anterolateral positions
- Grade 1: Painless, bleeding
- Grade 2: Prolapse with bowel movement (BM), spontaneously reduce
- Grade 3: Prolapse with BM, require manual reduction
- Grade 4: Chronically prolapsed, not reducible
ETIOLOGY
- Exact cause unknown
- Gravitational forces and abdominal pressure cause distention of the sinusoids
- Associated with straining and irregular bowel habits:
- Hard, bulky stools or diarrhea cause tenesmus/straining.
- Push anal cushions out of anal canal
- Weaken submucosal tissue leading to prolapse
- Higher resting anal pressures:
- Heredity:
- Absence of valves in veins
- Increased intra-abdominal pressure:
- Portal hypertension
DIAGNOSIS
SIGNS AND SYMPTOMS
- Painless, rectal bleeding with defecation
- Blood on stool or toilet paper
- Bright red blood drips into toilet bowel
- Rectal discomfort or pressure
- Severe pain if:
- Internal hemorrhoids prolapse and strangulate
- External thrombosed hemorrhoids
- Pruritus ani
- May also have fissure
History
- Length of bleeding
- Associate pain
- New lumps or masses by rectum
- Stool consistency: Hard or liquid
- Previous history of rectal problems
- Stool caliber
Physical-Exam
- Exam of perianal area:
- Gently spread buttocks.
- Discrete, dark blue, tender mass covered with skin: Thrombosed external hemorrhoid:
- Can have internal component
- Purplish, tender mucosal covered mass: Prolapsed, strangulated internal hemorrhoid:
- Usually associated with enlarged, thrombosed external hemorrhoid
- Have patient bear down to check for prolapsing hemorrhoids.
- Digital rectal exam mandatory to rule out cancer
- Anoscopy to visualize anal canal:
- Identify bleeding internal hemorrhoids.
ESSENTIAL WORKUP
Detailed history with thorough anorectal exam
DIAGNOSIS TESTS & NTERPRETATION
Lab
- CBC if history of significant blood loss:
- Platelet count
- PT/PTT/INR if patient on anticoagulants or severe comorbid condition
DIFFERENTIAL DIAGNOSIS
- Rectal prolapse
- Anal fissure
- Perirectal abscess/fistula
- Condyloma acuminate
- Carcinoma or melanoma
TREATMENT
PRE HOSPITAL
Establish IV access if severe bleeding
INITIAL STABILIZATION/THERAPY
Direct digital pressure to control bleeding
ED TREATMENT/PROCEDURES
- Conservative therapy for all patients:
- Hot sitz baths for 15 min TID and after each BM
- High-fiber diet—30 g/day:
- Eat more fresh fruits and vegetables.
- Increase bran intake.
- 10–12 glasses of water per day
- Stool softeners
- Bulk-forming laxatives
- NSAIDs: Analgesic and anti-inflammatory effects
- Excise thrombosed external hemorrhoid if severe pain, <5 days old and clot not resolving:
- Follow with conservative therapy.
- Place patient in prone jackknife position or left lateral decubitus and tape buttocks apart
- Infiltrate surrounding skin and underneath clot using 27G needle with lidocaine-containing epinephrine.
- Make an elliptical incision to excise clot/skin.
- May need silver nitrate sticks for hemostasis
- Place a small piece of Gelfoam and/or gauze onto the wound and tape.
- Remove dressing at time of 1st sitz bath in about 6 hr
- Give analgesics:
- NSAIDs
- Acetaminophen
- Lidocaine 5% ointment to anus: Topical anesthetic for pain relief
- 0.2% topical nitroglycerin ointment to anus—decreases pain by inhibiting sphincter spasm
- Manually reduce nonthrombosed, prolapsed internal hemorrhoids:
- Follow with conservative therapy.
- May need topical anesthetic or anal sphincter block with local anesthesia
- Can sclerose bleeding internal hemorrhoids with 2.5% sodium morrhuate or 3% hypertonic saline
- Can rubber band ligate 1 or 2 internal hemorrhoids:
- Avoid in immunocompromised patients due to perineal sepsis
- Nonreducible internal hemorrhoids:
- Nonstrangulated: Conservative management and surgical referral
- Strangulated: Immediate surgical referral for excision
Pregnancy Considerations
- Usually become symptomatic in the 3rd trimester and can be treated conservatively.
- Do not use Analpram-HC (class C)
MEDICATION
- Acetaminophen: 325–650 mg (peds: 15 mg/kg) with codeine 15–30 mg (peds: 0.5 mg/kg) PO q4h PRN
- Bran/fiber: 20 g PO daily
- Docusate sodium (Colace): 50–200 mg (peds: <3 yr, 10–40 mg/d; 3–6 yr, 20–60 mg/d; >6–12 yr, 40–150 mg/d) PO q12h
- ELA-Max 5 (5% lidocaine anorectal cream): Apply to perianal area q4h PRN pain (peds: not for <12 yr of age). Caution: Use very small amount; this product contains about 5 g lidocaine/100 g cream and is readily absorbed.
- Hydrocortisone/pramoxine topical (Analpram-HC) 1%/1% cream; 2.5%/1% cream/lotion (peds: Same dosing) apply thin amount to area TID–QID
- Hydrocortisone/lidocaine topical (AnaMantle HC) 0.5%/3% cream; 2.5%/3% gel (peds: Not indicated) apply to anal canal BID
- Ibuprofen (Motrin): 400–600 mg (peds: 40 mg/kg/d) PO q6h
- Nitroglycerin 0.2% ointment: Apply to area TID with cotton-tipped applicator
- Psyllium seeds: 1–2 tsp (peds: 0.25–1 tsp/d) PO q24h
FOLLOW-UP
DISPOSITION
Admission Criteria
- Strangulated grade 4 hemorrhoids:
- Surgical consult for prolapsed, thrombosed internal hemorrhoids
- Severe anemia with bleeding hemorrhoids
- Severe bleeding hemorrhoid in pt on anticoagulation or with portal hypertension
Discharge Criteria
Most patients will go home
Issues for Referral
Surgical referral for:
- Grade 3 or 4 internal hemorrhoids
- Suspected anorectal or colonic tumors, inflammatory bowel disease, coagulopathy, pregnancy, or immunocompromised
FOLLOW-UP RECOMMENDATIONS
- Colorectal follow up for grade 3 or 4 internal hemorrhoids or suspected tumor
- Primary care follow-up for uncomplicated hemorrhoids.
ALERT
All patients with bright red blood per rectum should be referred to GI or colorectal surgery to r/o malignancy
PEARLS AND PITFALLS
Hemorrhoids are not the only cause of anorectal pain and bleeding. Investigate for other etiologies when indicated.
ADDITIONAL READING
- Acheson AG, Scholefield JH. Management of hemorrhoids.
BMJ.
2008;336(7640):380–383.
- Kaider-Person O, Person B, Wexner SD. Hemorrhoidal disease.
J Am Coll Surg.
2007;204(1);102–117.
- Lohsiriwat V. Hemorrhoids: From basic pathophysiology to clinical management.
World J Gastroenterol
. 2012;18(17):1009–1017.
- Wexner SD, Pemberton JH, Beck DE, et al., eds.
The ASCRS Textbook of Colon and Rectal Surgery
. New York, NY: Springer; 2007.
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