Physical-Exam
- Vital signs
- Airway
- Mental status
- Cardiopulmonary exam
- Dermatologic exam, foreign bodies, cellulitis, blistering
ESSENTIAL WORKUP
- Careful history, repeated evaluation of wound sites
- Assessment of ABCs
DIAGNOSIS TESTS & NTERPRETATION
Lab
- CBC
- Electrolytes, BUN, creatinine, and glucose levels
- LFT
- Urinalysis
- Arterial blood gases if severe symptoms
Imaging
Soft tissue radiographs to detect foreign body
DIFFERENTIAL DIAGNOSIS
- Allergic reaction
- Cellulitis
- Gastroenteritis
- Aspiration pneumonia
- Near drowning
TREATMENT
PRE HOSPITAL
- Remove victim from water source.
- Control airway, breathing.
- Control hemorrhage.
- Detoxify venom with proper wound irrigation as discussed below.
INITIAL STABILIZATION/THERAPY
- Airway, breathing, and circulation management (ABCs)
- Establish IV access with 0.9% normal saline (NS).
ED TREATMENT/PROCEDURES
- General:
- Prepare for anaphylactic reactions (epinephrine/steroids).
- Prepare for intubation if needed.
- Diphenhydramine for itch, burn, hives
- Tetanus prophylaxis
- Corticosteroids for severe local reactions
- Narcotic analgesia for severe pain
- Antibiotic prophylaxis for the following:
- Large lacerations or burns
- Deep puncture wounds
- Grossly contaminated wounds
- Elderly or chronically ill
- Antibiotic choices:
- Trimethoprim/sulfamethoxazole (TMP-SMX; Bactrim)
- Tetracycline
- Ciprofloxacin
- 3rd-generation cephalosporin
- Sponges:
- Gently dry skin and remove spicule:
- Adhesive tape may aid in removal.
- 5% acetic acid (vinegar) (or 40–70% isopropyl alcohol) soaks QID for 10–30 min
- Coelenterates (Cnidaria jellyfish):
- Rinse wound with salt water or seawater:
- Hypotonic (fresh or tap water solutions), trigger more nematocysts
- Do not rub skin to avoid release of nematocysts.
- Inactivate toxin with 30-min soak of 5% acetic acid (vinegar)
- Remove remaining nematocysts with razor, clam shell.
- Apply topical anesthetics once nematocysts are removed.
- Sea Safe jellyfish sunblock products are available.
- Box-jellyfish sting envenomation (Australia) emergent cases:
- Administer
Chironex
antivenin: 1 amp (20,000 U) IV diluted 1:5 with crystalloid.
- Corticosteroids for severe reactions
- Starfish:
- Immerse in nonscalding hot water for pain relief.
- Irrigate and explore all puncture wounds.
- Prophylactic antibiotics for significant wounds
- Sea urchins:
- Immerse in nonscalding hot water for pain relief.
- Remove any remaining spines.
- Prophylactic antibiotics for significant wounds.
- Sea cucumbers:
- Immerse in nonscalding hot water for pain relief.
- 5% acetic acid soaks
- Ocular involvement:
- Proparacaine for pain
- Copious irrigation with NS
- Careful slit-lamp exam
- Cone shells:
- Hot water immersion for pain relief
- Be prepared for cardiac or respiratory support.
- Stingrays:
- Copious irrigation with removal of any visible spines
- Local suction is controversial.
- Hot water soaks for pain relief
- Narcotics for pain control
- High incidence of bacterial infection:
- Administer prophylactic antibiotics for significant wounds.
- Scorpion fish:
- Hot water soaks for pain relief and venom inactivation
- Copious irrigation, removal of any visible spines
- Local lidocaine or regional block for severe pain
- Surgical exploration for deep penetration/foreign bodies
- Stonefish antivenin for severe envenomations:
- One 2-mL amp diluted in 50-mL saline IV slow
- May cause serum sickness
- Catfish:
- Hot water soaks for pain relief and venom inactivation
- Copious irrigation, removal of any visible spines
- Consider local lidocaine, regional block, or narcotics for severe pain.
- Surgical exploration for deep penetration, foreign bodies
- Leave puncture wounds open to heal.
- Consider prophylactic antibiotics for hand, foot, or deep wounds.
- Sea snakes:
- Immobilize bitten extremity.
- Apply pressure bandage for venous occlusion (pre-hospital).
- Keep victim warm and still.
- Polyvalent sea snake antivenin reduces mortality to 3%:
- May require 3–10 amps (1000 U each)
- Prepare early for assisted ventilation.
MEDICATION
- Cefixime: 400 mg (peds: 8 mg/kg/24h) PO daily
- Ciprofloxacin: 500 mg PO BID
- Epinephrine: 0.3–0.5 mL SC 1:1,000 (peds: 0.01 mL/kg)
- Tetracycline: 500 mg PO QID (caution with photosensitivity)
- TMP-SMX (Bactrim DS): 1 tab [peds: 5 mg liquid (40/200/5 mL)/10 kg per dose] PO BID (caution with photosensitivity)
FOLLOW-UP
DISPOSITION
Admission Criteria
Significant signs of systemic involvement or need for antivenom administration
Discharge Criteria
No signs of systemic illness after 8 hr of observation
Issues for Referral
Zoos, aquariums for available supplies of antivenom; poison control centers: 800-222-1222
PEARLS AND PITFALLS
- Most toxins are detoxified with either temperature change (hot water) or pH alteration (more acidic).
- Specific antivenoms for box jellyfish, stone fish, and sea snake envenomations are available but in limited supply; acquire early in treatment course.
ADDITIONAL READING
- Avelino-Silva VI, Avelino-Silva T. Images in clinical medicine.
Evolution of a jellyfish sting. N Eng J Med
. 2011;365(3):251.
- Balhara KS, Stolbach A. Marine envenomations.
Emerg Clin North Am.
2014;32(1):223--243.
- Fernadez I, Vallalolid G, Varon J, et al. Encounters with venomous sea life.
J Emerg Med.
2011;40(1):103--112.
CODES
ICD9
- 692.89 Contact dermatitis and other eczema due to other specified agents
- 989.5 Toxic effect of venom
ICD10
- T63.511A Toxic effect of contact with stingray, accidental (unintentional), initial encounter
- T63.621A Toxic effect of contact with other jellyfish, accidental (unintentional), initial encounter
- T63.691A Toxic effect of contact with other venomous marine animals, accidental (unintentional), initial encounter
MASTITIS
Hao Wang
•
Marco Coppola
BASICS
DESCRIPTION
- Infection of the breast causing pain, swelling, and erythema
- Most commonly in women who are breast-feeding
- Often with systemic symptoms also:
- Incidence may be as high as 33% in lactating woman
- Onset typically 2–3 wk to months postpartum
- 75–95% occur before infant is 3 mo old
- Rare during 1st postpartum week
- More common in advanced maternal age and patients with diabetes
- Complications:
- Recurrence
- Abscess
- Sepsis
- Necrotizing fasciitis
- Fistula
- Scarring
- Breast hypoplasia
Pediatric Considerations
Can occur in full-term infants <2 mo of age
ETIOLOGY
- Staphylococcus aureus
most common
- Less common causes:
- Coagulase-negative
Staphylococcus
- Streptococcus
spp.
- Escherichia coli
- Haemophilus influenzae
- Candida albicans
- Risk factors:
- Cleft lip or palate
- Cracked nipples
- Infant attachment issues
- Local milk stasis
- Nipple piercing
- Poor maternal nutrition
- Previous mastitis
- Primiparity
- Restriction from a tight bra
- Sore nipples
- Short frenulum in infant
- Use of a manual breast pump
- Yeast infection