Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1031 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
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   Hemosiderosis of excessive iron intake (e.g., repeated blood transfusions, iron therapy, iron-containing vitamins) (may be >300 μg/dL)
   Decreased formation of RBCs (e.g., thalassemia, pyridoxine deficiency anemia, PA in relapse)
   Increased destruction of RBCs (e.g., hemolytic anemias)
   Acute liver damage (degree of increase parallels the amount of hepatic necrosis) (may be >1,000 μg/dL); some cases of chronic liver disease
   Progesterone birth control pills (may be >200 μg/dL) and pregnancy
   Premenstrual elevation by 10–30%
   Acute iron toxicity; serum iron-to-TIBC ratio is not useful for this diagnosis
   Repeated transfusions
   Lead poisoning
   Acute hepatitis
   Vitamin B
6
deficiency

Decreased In

   Iron deficiency anemia
   Normochromic (normocytic or microcytic) anemias of infection and chronic diseases (e.g., neoplasms, active collagen diseases)

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