Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1045 page)

   Monitoring of metabolic acidosis, lactic acidosis

   Interpretation

Increased In

   Hypoperfusion: CHF, shock

   Decrease oxygen content: hypoxemia, severe anemia, carbon monoxide poisoning

   Sepsis

   DKA

   Drugs and toxins (e.g., Ringer lactate solution, biguanides, retroviral therapy, isoniazid, acetaminophen, ethanol, ethylene glycol, and others)

   Strenuous exercise

   Seizures

   Liver failure

   Kidney failure

   
D
-Lactate acidosis (due to short bowel syndrome or other forms of malabsorption)

   Inborn errors of metabolism (e.g., pyruvate dehydrogenase deficiency, glycogen storage disease)

   Limitations