Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (967 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
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   Use
   Ketamine: induction of anesthesia
   Phencyclidine: no current medical use in the United States; abused as a hallucinogen
   LSD: no current medical use in the United States; abused as a hallucinogen
   Limitations
   LSD unstable in light, elevated temperature, and alkaline conditions and may irreversibly adsorb to containers.
   
Screening:
individual drug-specific tests required; immunoassay based on automated chemistry analyzers using blood/serum/urine
   Ketamine
   No tests currently available by immunoassay
   TLC procedures have a high limit of detection of approximately 1,000 ng/mL.
   See confirmation: readily detected with alkaline liquid–liquid or solid-phase extraction followed by gas chromatography or GC/MS analysis.
   PCP
   Tests available from multiple manufacturers

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