19
Connaught drops out:
M. H. Smith, “National Childhood Vaccine Injury Compensation Act,”
Pediatrics
82 (1988): 264-269.
20
James Mason testifies:
Testimony before the Subcommittee on Health and the Environment, Committee on Energy and Commerce, U.S. House of Representatives, December 19, 1984.
20
AAP emergency meeting:
“DTP Vaccine Shortage,” Summary of February 12, 1985, meeting hosted by the AAP; summary generously provided by Dr. Bruce Weninger, CDC.
20
Kevin Toner:
Toner v. Lederle Laboratories
, 112 Idaho 328.
20
Lederle drops out:
M. H. Smith, “National Childhood Vaccine Injury Compensation Act,”
Pediatrics
82 (1988): 264-269.
21
Companies stop making other vaccines:
Ibid.
21
Congress passes National Childhood Vaccine Injury Act:
Allen,
Vaccine
, 286.
21
Reagan signs bill into law:
Ibid., 287.
21
Vaccine Injury Compensation Program:
E. W. Kitch, G. Evans, and R. Gopin, “U.S. Law,” in
Vaccines
, 3rd ed., eds. S. A. Plotkin and W. A. Orenstein (Philadelphia: W. B. Saunders, 1999).
21
Edward Brandt:
Quoted in Allen,
Vaccine
, 281.
22
AMA dissatisfied:
Ibid., 282.
22
Henry Waxman:
Quoted in Colgrove,
State of Immunity
, 215.
22
Decline in lawsuits:
E. W. Kitch, G. Evans, and R. Gopin, “U.S. Law,” in
Vaccines
, 3rd ed., eds. S. A. Plotkin and W. A. Orenstein (Philadelphia: W. B. Saunders, 1999).
3. A Crude Brew
25
Gordon Stewart regarding crude brew:
DPT: Vaccine Roulette
, WRC-TV, Washington, D.C., April 19, 1982.
25
Kendrick and Eldering vaccine:
P. Kendrick, G. Eldering, and A. Borowski, “A Study in Active Immunization Against Pertussis,”
American Journal of Hygiene
29 (1939): 133-153.
26
Pertussis proteins:
K. M. Edwards and M. D. Decker, “Pertussis Vaccines,” in
Vaccines
, 5th ed., eds. S. A. Plotkin, W. A. Orenstein, and P. A. Offit (London: Elsevier/Saunders, 2008).
26
Immunological challenges in vaccines:
P. A. Offit, J. Quarles, M. A. Gerber, et al., “Addressing Parents’ Concerns: Do Multiple Vaccines Overwhelm or Weaken the Infant’s Immune System?”
Pediatrics
109 (2002): 124-129.
27
Larry Baraff regarding reason for study:
DPT: Vaccine Roulette
, WRC-TV, Washington, D.C., April 19, 1982.
27
Baraff study:
C. L. Cody, L. J. Baraff, J. D. Cherry, et al., “Nature and Rates of Adverse Reactions Associated with DTP and DT Immunizations in Infants and Children,”
Pediatrics
68 (1981): 650-660.
28
Baraff regarding safer vaccine:
DPT: Vaccine Roulette
, WRC-TV, Washington, DC, April 19, 1982.
29
Geier paper:
M. R. Geier, H. Stanboro, and C. R. Merril, “Endotoxin in Commercial Vaccine,”
Applied Environmental Microbiology
36 (1978): 445-449.
29
Endotoxin:
T. Gutsmann, A. B. Schromm, and K. Brandenburg, “The Physicochemistry of Endotoxins in Relation to Bioactivity,”
International Journal of Medical Microbiology
297 (2007): 341-352; S. M. Opal, “The Host Response to Endotoxin, Antilipopolysaccharide Strategies, and the Management of Severe Sepsis,”
International Journal of Medical Microbiology
297 (2007): 365-377; S. F. Lowry, “Human Endotoxemia: A Model for Mechanistic Insight and Therapeutic Targeting,”
Shock
24 (2005): 94-100.
29
Medical Research Council study:
S. Bedson et al., “Vaccination Against Whooping Cough: Report to the Medical Research Council,”
British Medical Journal
2 (1956): 454-462.
29
EEG study:
B. Hellström, “Electroencephalographic Studies in Triple-Immunized Infants,”
British Medical Journal
2 (1962): 1089-1091.
29
North West Thames Region study:
T. M. Pollack and J. Morris, “A 7-Year Survey of Disorders Attributed to Vaccination in North West Thames Region,”
The Lancet
1 (1983): 753-757.
30
Neuropathological study:
J.A.N. Corsellis, I. Janoti, and A. K. Marshall, “Immunization Against Whooping Cough: A Neuropathological Review,”
Neuropathology and Applied Neurobiology
9 (1983): 261-270.
30
Denmark study:
W. D. Shields, C. Nielson, D. Buch, et al., “Relationship of Pertussis Immunization to the Onset of Neurologic Disorders: A Retrospective Epidemiologic Study,”
Journal of Pediatrics
113 (1988): 801-805.
30
Group Health Cooperative study:
A. M. Walker, H. Jick, D. R. Perera, et al., “Neurologic Events Following Diphtheria-Tetanus-Pertussis Immunization,”
Pediatrics
81 (1988): 345-349.
30
Griffin study:
M. R. Griffin, W. A. Ray, E. A. Mortimer, et al., “Risk of Seizures and Encephalopathy After Immunization with the Diphtheria-Tetanus-Pertussis Vaccine,”
Journal of the American Medical Association
263 (1990): 1641-1645.
30
British Pediatric Association and Canadian National Advisory Committee on Immunization:
J. D. Cherry, “Pertussis Vaccine Encephalopathy: It Is Time to Recognize It as the Myth That It Is,”
Journal of the American Medical Association
263 (1990): 1679-1680; Canadian National Advisory Committee on Immunization, Minister of National Health and Welfare, National Advisory Committee on Immunization,
Canadian Immunization Guide
, 3rd ed. (Ottawa, Canada: Minister of National Health and Welfare, Health Protection Branch, 1989), 78-83.
31
Copenhagen study:
T. Madsen, “Vaccination Against Whooping Cough,”
Journal of the American Medical Association
101 (1933): 187-188.
31
Golden review:
G. S. Golden, “Pertussis Vaccine and Injury to the Brain,”
Journal of Pediatrics
116 (1990): 854-861. Italics added for emphasis.
31
James Cherry and myth:
J. D. Cherry, “Pertussis Vaccine Encephalopathy: It Is Time to Recognize It as the Myth That It Is,”
Journal of the American Medical Association
263 (1990): 1679-1680.
31
Institute of Medicine report:
Institute of Medicine,
Adverse Effects of Pertussis and Rubella Vaccines: A Report of the Committee to Review the Adverse Consequences of Pertussis and Rubella Vaccines
(Washington D.C.: National Academies Press, 1991).
31
Child Neurology Society report:
Ad Hoc Committee for the Child Neurology Consensus Statement on Pertussis Immunization and the Central Nervous System, “Pertussis Immunization and the Central Nervous System,”
Annals of Neurology
29 (1991): 458-460.
31
University of Washington/CDC study:
J. L. Gale, P. B. Thapa, S.G.F. Wassilak, et al., “Risk of Serious Acute Neurological Illness After Immunization with Diphtheria-Tetanus-Pertussis Vaccine: A Population-Based Case-Control Study,”
Journal of the American Medical Association
271 (1994): 37-41.
31
Revision of VICP table:
G. Evans, E. M. Levine, and E. H. Saindon, “Legal Issues,” in
Vaccines
, 5th ed., eds. S. A. Plotkin, W. A. Orenstein, and P. A. Offit (London: Elsevier/Saunders, 2008); 60 Fed. Reg. 7678, 7691 (February 8, 1995).
32
Computerized records study:
W. E. Barlow, R. L. Davis, J. W. Glasser, et al. for the Centers for Disease Control and Prevention Vaccine Safety DataLink Working Group, “The Risk of Seizures After Receipt of Whole-Cell Pertussis or Measles, Mumps, and Rubella Vaccine,”
New England Journal of Medicine
345 (2001): 656-661.
32
Febrile seizures:
M. D. Blumstein and M. J. Friedman, “Childhood Seizures,”
Emergency Medicine Clinics of North America
25 (2007): 1061-1086.
32
Miller study:
D. L. Miller, E. M. Ross, R. Alderslade, et al., “Pertussis Immunization and Serious Acute Neurological Illness in Children,”
British Medical Journal
282 (1981): 1595-1599.
33
Bonthrone trial:
“Parents Fail in Whooping Cough Vaccination Test Case,”
The Times
(London), August 31, 1985.
33
Johnnie Kinnear’s symptoms:
B. Deer, “The Vanishing Victims: Can Whooping Cough Jabs Cause Brain Damage in Children?”
Sunday Times Magazine
(London), November 1, 1998.
34
Kinnear lawsuit:
“The Law Tries to Decide Whether Whooping Cough Vaccine Causes Brain Damage: Professor Gordon Stewart Gives Evidence,”
British Medical Journal
292 (1986): 1264-1266.
34
Stuart-Smith and the Hillsborough soccer tragedy:
D. Conn, “Hillsborough: How Stories of Disaster Police Were Altered,”
The Guardian
, April 13, 2009.
34
Stewart at Kinnear trial:
“The Law Tries to Decide Whether Whooping Cough Vaccine Causes Brain Damage: Professor Gordon Stewart Gives Evidence,”
British Medical Journal
292 (1986): 1264-1266.
34
Kinnear hospital records:
B. Deer, “The Vanishing Victims: Can Whooping Cough Jabs Cause Brain Damage in Children?”
Sunday Times Magazine
(London), November 1, 1998.
34
Stuart-Smith regarding mother’s testimony in Kinnear trial:
Stuart-Smith, Lord Justice, Judgment 30 March 1988,
Loveday v. Renton and the Wellcome Foundation Ltd.
, Chilton Vint & Co, 24 Chauncery Lane, London, WC2.
35
Stewart misrepresents Miller study:
“The Law Tries to Decide Whether Whooping Cough Vaccine Causes Brain Damage: Professor Gordon Stewart Gives Evidence,”
British Medical Journal
292 (1986): 1264- 1266.
35
Levine and Wenk quote:
Ibid.
35
Machin-Stewart interchange:
B. Deer, “The Vanishing Victims: Can Whooping Cough Jabs Cause Brain Damage in Children?”
Sunday Times Magazine
(London), November 1, 1998.
35
“An evidential liability”:
Stuart-Smith, Lord Justice, Judgment 30 March 1988,
Loveday v. Renton and the Wellcome Foundation Ltd.
, Chilton Vint & Co, 24 Chauncery Lane, London, WC2.
35
Loveday trial:
Stuart-Smith, Lord Justice, Judgment 30 March 1988,
Loveday v. Renton and the Wellcome Foundation Ltd.
, Chilton Vint & Co, 24 Chauncery Lane, London, WC2.
35
Susan Loveday’s story:
C. Dyer, “Whooping Cough Vaccine on Trial Again,”
British Medical Journal
295 (1987): 1053-1054.
36
Loveday’s story unravels:
B. Deer, “The Vanishing Victims: Can Whooping Cough Jabs Cause Brain Damage in Children?”
Sunday Times Magazine
(London), November 1, 1998.
36
Loveday trial:
C. Bowie, “Lessons from the Pertussis Vaccine Court Trial,”
The Lancet
335 (1990): 397-399; all quotes from the Loveday trial were obtained from Stuart-Smith, Lord Justice, Judgment 30 March 1988,
Loveday v. Renton and the Wellcome Foundation Ltd.
, Chilton Vint & Co, 24 Chauncery Lane, London, WC2.
39
David Miller’s study falls apart:
J. D. Cherry, “The Epidemiology of Pertussis and Pertussis Immunization in the United Kingdom and the United States: A Comparative Study,”
Current Problems in Pediatrics
14 (1984): 7-77; J. D. Cherry, “Recurrent Seizures After Diphtheria, Tetanus, and Pertussis Immunization,”
American Journal of Diseases in Children
138 (1984): 904-907; J. D. Cherry, P. A. Brunell, G. S. Golden, and D. T. Karzon, “Report of the Task Force on Pertussis and Pertussis Immunization—1988,”
Pediatrics
81 (1988): 933-984; J.B.P. Stephenson, “A Neurologist Looks at Neurological Disease Temporally Related to DTP Immunization,”
Tokai Journal of Experimental and Clinical Medicine
13 (1988): 157-164.
39
Salisbury on Stuart-Smith verdict:
Author interview with David Salisbury, November 30, 2009.
39
Canadian verdict:
Rothwell v. Connaught Laboratories
, Supreme Court of Ontario, June 17, 1988.