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Authors: Aarathi Prasad

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ACKNOWLEDGEMENTS

This book would not have been possible without the help and support of many people. I am indebted to you.

For inspiration, for your ears and eyes, for being intrepid archaeologists of obscure journals, for helping me pin down the science, and for your patience and many kindnesses: Professor Armand
Leroi, Nalini Persad, Lynn Saliba, Dr Robin Lovell-Badge, Dr Evan Harris, Anjali Bhargava, Amanda Hargreaves, Frank Swain, Jessica Hamzelou, Dr Abul Tarafder, Dr David Mann, Mira Samlal and Surian
Fletcher-Jones. For sharing your ideas on (some particularly difficult) ethics: Dr Anna Smajdor, Dr John Harris, and Clare Lewis-Jones MBE. For leisurely lunches in the once all-male common room at
UCL, sharing J. B. S. Haldane stories and monographs, and contemplating the reproductive biology of the Blessed Virgin: Professor Sam Berry. For fascinating medical and scientific discussions:
Professor Darren Griffin, Professor Karim Nayernia, Dr Olga Kapellou, and Dr Allan Pacey.

My very special thanks also to: Professor John Wood, whom I befriended on a flight to the Bahamas and who quite literally changed the course of my life; Peter Tallack, my literary agent; Marsha
Fillion, who commissioned this book while at Oneworld, and my editor, Robin Dennis, who is pure genius; Tara Lumley-Savile, for putting up with me as I worked mornings, evenings, and weekends
instead of doing fun things with you like the other mums – my deepest gratitude to you also because you sparked the idea that made me start this book; and Dr João Medeiros, who made me
finish it. Thank you, thank you.

INDEX

abortion

adoptions

Aeschylus

African bat bug

AIDS

Al-Jahiz

Alexander the Great

American Civil War

amino acids

An Account of the Breeding of Worms in Human Bodies

Andry, Nicolas

Angelman syndrome

aphids, reproduction

Aristotle

on atomism

on fertility

On the Generation of Animals

Aristotle’s Masterpiece

ART (assisted reproductive technology)

artificial insemination

artificial life form, first

Asia Minor

atomism

autism

bacteria

enterobacteria

Mycoplasma genitalium

Salmonella typhi

Wolbachia

Baer, Karl Ernst von

Balfour-Lynn, Stanley Dr

Bartholin, Thomas

Beckwith-Wiedemann

bees

Beneden, Edouard Van

Berry, Sam

Bhalla-Pentley, Melissa

biological parent, redefining

bipolar affective disorder

birds

birth defects

Bland, Kim

Blyth, Professor Eric

Bosch, Hieronymous

BrannstrÖm, Mats

British Fertility Society

Bronze Age

Brown, Lesley

Brown, John

Brown, Louise Joy

Brown, Natalie

Brown University

Budin, Pierre-Constant

Buley, Kevin

Bulletti, Professor Carlo

Bunker, Chang and Eng

Butscher, Susanne

Buttle, Elizabeth

Caesarean sections

cancer

Campbell, Kathleen

Carson, Sandra

Celera Genomics

cells

copying

germ

red blood

Sertoli

chickens

chlamydia

chromosomes

abnormalities

deterioration of Y

X

XO

XY

XX

XXX

XXXX

Y

clitoris

cloning

contraceptives

coronary heart disease

cot death syndrome

CSF (cytostatic factor)

Couney, Dr Martin Arthur

cystic fibrosis

cytoplasm

Daily Mail

Daily Telegraph

Dalenpatius

Darwin, Charles

de la Chapelle syndrome

De Temperamentis

de Villeneuve

diabetes

Dor Yeshorim

DNA

CGG

Dlk1-Dio3

eggs, one set of

Fragile X

genetic diversity

human genome

isolating

misrepeating

of ovarian teratomas

Dolly the sheep

Down syndrome

drugs, misuse

dwarfism

eclampsia

pre-

ectogenesis

Edwards, Robert

eggs

and mammals

artificial

buying/trafficking

creating complete new being

dividing

donated

effects of ageing

first fertilized outside womb,

freezing

from stem cells

how develop in the body

numbers in females

one set of DNA

predisposed to X or Y

chromosomes

declining numbers in females

regulations concerning

when formed

women’s, and evolution

ejaculation

ejaculatory duct

electric ant

Ellis, Megan

embryo

Entozoa

epigeneics

epilepsy

eukaryote

European Parliament

Evening Standard

Evening News

Experiments Conerning the Generation of Animals

Fageeh, Dr Wafa

Fallopian tubes

families, biological

fertility

declining rates

Fertility First

foetal alcohol syndrome

foetus

Folge, C.

follicles

Fragile X syndrome

Francis I

frogs

fruit fly

FSH (follicle stimulating hormone)

Galen, Aelius

De Temperamentis

Galilei, Galileo

Gardianul

gene therapy

genes

BRCA1

cftr

c-mos

disorders

Dlk1-Dio3

effects on woman’s fertility & sterility

EYCL3

expression

FMR1

H19

IGF2

mhc

PEG

recessive

SOX9

SRY

syncytin

geneticists

genetics

genomes

genomic imprinting

Girault

GnRH (gonadotropin-releasing hormone)

Gould, Stephen Jay

green swordtail

Guardianul

Hackney

Haldane, J.B.S.

Ham, Johan

Hamilton, E.D.

‘Hapsburg jaw’

Hartsoeker, Niklaas

Harvey, William

Hawkes, Kristen

HCG (human chorionic gonatrophin hormone)

Henry II

Henry IV

Henry Doorly Zoo, Nebraska

Heredity and Politics

hermaphroditism

Herodotus

Herophilos

Hippocrates

HIV

Hohenheim, Phillipus Bombastus von

HPA (hypothalamic-pituitary-adrenal axis)

Human Fertilisation and Embryology Authority

Human Genome Project

Hunter, John

Huntington’s disease

Huxley, Thomas Henry

hyenas

ICSI (intrra-cytoplasmic sperm injection)

immune system

imprinting

inbreeding

incubators

Independent

infertility

INSERM

insulin

in vitro-derived cells

Islam, medieval, biological ideas

IUI (intra uterine insemination)

IVF (in vitro fertilization)

Catholic opposition to

first IVF baby

James I

Japanese Ryukyu spiny rat

Jefferson Medical College

Jones, Emmimarie

Jones, Jayne

Jones, Monica

Journal of Virology

Kaguya the mouse

Kitab al-Hayawan

kleptogenesis

Klinefelter syndrome

Komodo dragons

Kono, Tomohiro

Kuwabara, Professor Yoshinori

ladybird beetles

Leeuwenhoek, Antonie

Liu, Hung-Ching

lizards

Loeb, Jacques

London Zoo

Lozada, Dr. Géado

maize

malaria

male pregnancy

Male Nipples and Clitoral Ripples

mammals

Marfan syndrome

Marie Claire

marine species

Markert, Clement

Marmot, Sir Michael

marriages, consanguineous

marsupials

Masui, Yoshio

Mayer-Rokitansky-Küster-Hauser syndrome

Mayr, Ernst

Medici, Catherine de

Medina, Lina

meiosis

melanocortin

menopause

MHC molecules

mice

microscopes

miscarriage

mitosis

mole vole

molecules, MHC

mosquito

Mosuo

mothers, and bonding

moths

MPF (maturation promoting factor)

mutations

natural selection

Nature Genetics

Neesen, Dr Victor

New South Wales Department of

Primary Industries

New York Times

NHS

North East England Stem Cell Institute

nucleotides

Observer

obesity

oestradiol

oestrogen

Office for National Statistics (UK)

study of lone parents

OHSS (ovarian hyperstimulation syndrome)

Oldham and District General Hospital

On a True Parthenogenesis

On the Generation of Animals

On Viruses, Sex and Motherhood

‘oral conception’

Origen

Ottosson, Eva

Ottosson, Sara

Otway, Nick

ovarian teratomas

ovaries

cancer

cyst

first artificial

tumour

transplants

oxytocin

Owen, Richard

Pacey, Dr Allan

Palais de Beaux Arts

Pancoast, Professor William

Paracelsus

paradox of sex

parasites

Ascaris megalocephala

fetus-in-fetu

Ichthyophonus hoferi

malarial

Mycoplasma genitalium

Plasmodium

Wolbachia

parents, single

parthenogenesis

in human beings (article)

penis

PGD (pre-implantation genetic diagnosis)

PGS (pre-implantation genetic screening)

phenylthiourea

PhilipII, King of Macedon

placenta

eating

Plantades, François de

Plato

Poitiers, Diane de

pregnancy

pregnancy hormone (hCG)

premature babies

brains

breathing problems

Charlotte Wyatt

Priore, Giuseppe Del

progesterone

protein

Queen Charlotte’s Hospital

rats

recessive disorders

Red Queen hypothesis

Renaissance

reproduction

advantages of sexual

and cultural values

and female’s age

and male’s age

declining rates

first life forms

future trends

mothers in their fifties

pre-17th century ideas on

post-17th century ideas on

pre-teen pregnancies

recipe for life

spermless

Royal College of Midwives

Ruakura Agriculture Centre

Savage, Caroline

Schenck, Professor Leopold

schizophrenia

semen

sex, problems for women

sharks

Sheffield University

Sherman, Jerome K.

Siebold, Karl Ernst von

Silber, Dr Sherman

Silver-Russell syndrome

Sims, James Marion

skin layers

Smellie, William

Smith, A.D.

Smith, Richard

snakes

Soranus

sperm

artificial

buying

considered parasite

creation of

donors

early research into

freezing/storing

from stem cells

internet sales

imaginary people in

legal regulations

rapid creation of

‘spermatic worms’

spermatozoa

spindle

Spurway, Helen

Spurway, Jack

SRY

SSC (spermatogonial stem cells)

STDs

stem cells

Steptoe, Dr Patrick

stingless wasp

stinkbugs

stress

Sudden Infant Death syndrome

Sunday Pictorial

surrogacy

tanning

Tarnier, Etienne Stéphane

Taylor, Amillia Sonja

Tehran University

teratomas

Testart, Jacques

test-tube babies

testosterone

Thabit ibn Qurra

thalassaemia

The Concert in the Egg

The Eumenides

The Lancet

Tokyo University of Agriculture

totipotency

Tourette’s syndrome

trophoblast

tuberculosis

turkeys

Turner’s syndrome

University College London

UCLA Medical Center

Universe

University of

Arkansas Medical Center

Bologna

California

Cambridge

Huddersfield

Utah

US Census Bureau

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