The Dog Cancer Survival Guide (134 page)

Animal Species in which N-nitroso compounds induce cancer. Bogovski P and Bogovski S.,
Int J Cancer
. 1981;27(4):471- 4.

N-nitroso compounds and human cancer: where do we stand? Bartsch H.,
IARC Sci Publ.
1991;(105):1-10. Review.

Inhibition of nitrosation. Bartsch H, et. al.,
Basic Life Sci
. 1993;61:27-44. Review.

Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC. Mirvish SS.,
Cancer Lett
. 1995 Jun 29;93(1):17-48. Review. Erratum in:
Cancer Lett
1995 Nov 6;97(2):271.

Production of dog food from protein meal obtained from processed poultry slaughter by-products. Slavko, F et al.
Acta agriculturae Serbica
2010, vol. 15, iss. 29, pp. 25-30

Genotoxic and carcinogenic risk to humans of drug-nitrite interaction products. Brambilla G and Martelli A.
Mutat Res
. 2007 Jan-Feb;635(1):17-52. Epub 2006 Dec 6. Review.

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis. Schut HA and Snyderwine EG.
Carcinogenesis
. 1999 Mar;20(3):353-68. Review.

Heterocyclic amines: Mutagens/carcinogens produced during cooking of meat and fish. Sugimura T, et. al.
Cancer Sci
. 2004 Apr;95(4):290-9. Review.

Comments on the history and importance of aromatic and heterocyclic amines in public health. Weisburger JH.
Mutat Res
. 2002 Sep 30;506-507:9-20.

Heterocyclic amines: Mutagens/carcinogens produced during cooking of meat and fish. Sugimura T, et. al.
Cancer Sci
. 2004 Apr;95(4): 290-9. Review.

A new approach to risk estimation of food-borne carcinogens-heterocyclic amines--based on molecular information. Nagao M.
Mutat Res
. 1999 Dec 16;431(1): 3-12. Review.

Garlic

Possible mechanism by which allyl sulfides suppress neoplastic cell proliferation. Knowles LM, Milner JA.
J Nutr
. 2001 Mar;131(3s):1061S-6S.

Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver. Arora A, Seth K and Shukla Y.
Carcinogenesis
. 2004 Jun;25(6):941-9. Epub 2004 Jan 16.

Antiproliferative effects of allium derivatives from garlic. Pinto JT and Rivlin RS.
J Nutr
. 001 Mar;131(3s):1058S-60S.

Garlic and cancer: a critical review of the epidemiologic literature. Fleischauer AT and Arab L.
J Nutr
. 2001 Mar;131(3s):1032S-40S.

Ginger

Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha, beta-unsaturated carbonyl group is a prerequisite. Murakami A, et al.
Carcinogenesis
. 2002 May;23(5):795-802.

Cancer preventive properties of ginger: a brief review. Shukla Y and Singh M.
Food Chem Toxicol
. 2007 May;45(5):683-90.

Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger. Surh YJ, et al.
J Environ Pathol Toxicol Oncol.
1999;18(2):131-9.

Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice. Park KK, et al.
Cancer Lett
. 1998 Jul 17;129(2):139-44. Erratum in:
Cancer Lett
1998 Sep 25;131(2):231.

Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Ernst E and Pittler MH.
Br J Anaesth
. 2000 Mar;84(3):367-71.

Cancer preventive properties of ginger: a brief review. Shukla Y and Singh M.
Food Chem Toxicol
. 2007 May;45(5):683-90.

Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. Black CD, Herring MP, Hurley DJ, O’Connor PJ.
J Pain.
2010 Sep;11(9):894-903.

Identification of serotonin 5-HT1A receptor partial agonists in ginger. Nievergelt A, Huonker P, Schoop R, Altmann KH, Gertsch J.
Bioorg Med Chem
. 2010 May 1;18(9):3345-51

Heartworm preventative and flea/tick control products

Spinosad insecticide: subchronic and chronic toxicity and lack of carcinogenicity in Fischer 344 rats. Yano BL, Bond DM, Novilla MN, McFadden LG, Reasor MJ.
Toxicol Sci.
2002 Feb;65(2):288-98.

Fipronil: environmental fate, ecotoxicology, and human health concerns. Tingle CC, et al.
Rev Environ Contam Toxicol
. 2003;176:1-66. Review.

Permrethrin
http://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+6790

Imidacloprid
http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35730I

Ivermectin
http://potency.berkeley.edu/chempages/IVERMECTIN.html

Selamectin
http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC41305

Nitenpyram
http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC43609

Hemangiosarcoma

Johnson KD Splenic Tumors, in Henry CJ, Higginbotham ML (ed):
Cancer Management in Small Animal Practice.
Missouri. Saunders Elsevier 2010, p 264-68.

Tumors of the Skin, Subcutis and other soft tissues. Northrup N, Geiger T, in Henry CJ, Higginbotham ML (ed):
Cancer Management in Small Animal Practice
. Missouri. Saunders Elsevier 2010, p 299.

Hemangiosarcoma. Chun R, in Cote E (2
^nd
ed),
Clinical Veterinary Advisor: Dogs and Cats
. Missouri, Mosby Elsevier, 2011, p 482-486.

Hemangiosarcoma, Cardiac. Edwards NJ, in Cote E (ed),
Clinical Veterinary Advisor: Dogs and Cats.
Missouri, Mosby Elsevier, 2007, p 473-75.

Miscellaneous Tumors. Thamm DH, in Withrow SJ, Vail DM (eds):
Withrow & MacEwen’s Small Animal Clinical Oncology
. Missouri, Saunders Elsevier, 2007, pp 785-823.

Hemangiosarcoma in dogs and cats. Smith A.
Vet Clin Small Anim
33:533-552, 2003.

Prevalence, type, and importance of splenic diseases in dogs:1,480 cases (1985-1989), Spangler WL, Culbertson MR.
J Am Vet Med Assoc
200:829, 1992.

Treatment of canine hemangiosarcoma: 2000 and beyond. Clifford CA, Mackin AJ, Henry CJ.
J Vet Intern Med
14:479, 2000.

Magnetic resonance imaging of focal splenic and hepatic lesions in the dog. Clifford CA, Pretorius ES, Weisse C et al.
J Vet Intern Med.
18(3):330-8. 2004\

Vascular endothelial growth factor concentrations in body cavity effusions in dogs. Clifford CA, Hughes D, Beal MW, et al.
J Vet Intern Med.
16(2):164-8. 2002

Ventricular arrhythmias in dogs with splenic masses. Keyes M, Rush J.
Vet Emerg Crit Care
3:33-38. 1994

Liposome-encapsulated muramyl tripeptide phosphatidylethanolamine adjuvant immunotherapy for splenic hemangiosarcoma in the dog: a randomized multi-institutional clinical trial. Vail DM, MacEwen EG, Kurzman ID, et al.
Clin Cancer Res
81:935, 1995.

Continuous low-dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs. Lana S, U’ren L, Plaza S, et al.
J Vet Intern Med
21:764, 2007.

Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy. Johnson KA, Powers BE, Withrow SJ, et al.
J Vet Intern Med
3:160, 1989.

Pathologic factors affecting postsplenectomy survival in dogs. Spangler WL, Kass PH.
J Vet Intern Med
11:166, 1997

Metastatic pattern in dogs with splenic hemangiosarcoma. Waters D, Hayden D, Walter P.
J Small Anim Pract
3:222, 1988.

Efficacy and toxicity of a dose-intensified doxorubicin protocol in canine hemangiosarcoma. Sorenmo KU, Beaz JL, Clifford CA, et al.
J Vet Intern Med
18:209-213, 2004

Canine hemangiosarcoma treated with standard chemotherapy and minocycline. Sorenmo K, Duda L, Barber L, et al.
J Vet Intern Med
. 14(4): 395-8. 2000

Evaluation of intracavitary mitoxantrone and carboplatin for treatment of carcinomatosis, sarcomatosis, and mesothelioma, with or without malignant effusions: a retrospective analysis of 12 cases (1997-2002). Charney SC, Bergman PJ, McKnight JA, et al.
Vet Comp Oncol
3:171, 2005.

Hemangiosarcoma: Cardiac

Cardiac tumors in dogs: 1982-1995. Ware WA, Hopper DL.
J Vet Intern Med
13:95, 1999.

Cardiac troponins I and T in dogs with pericardial effusion
.
Shaw SP, Rozanski EA, Rush JE.
J Vet Intern Med
; 18:322-324. 2004

Use of pericardial fluid pH to distinguish between idiopathic and neoplastic effusions. Fine DM, Tobias AH, Jacob KA.
J Vet Intern Med.
17:525-9. 2003

The diagnostic value of pericardial fluid pH determination. Edwards NJ.
J Am Anim Hops Assoc Intern Med.
32:63-67. 1996

Analysis of prognostic indicators for dogs with pericardial effusion: 46 cases (1985-1996). Dunning D, Monnet E, Orton EC, et al.
J Am Vet Med Assoc
. 212:1276-80. 1998

Cardiac hemangiosarcoma in the dog: a review of 38 cases. Aronsohn M.
J Am Vet Med Assoc
187:922, 1985.

Survival times in dogs with right atrial hemangiosarcoma treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986-2000). Weisse C, Soares N, Beal MW, et al.
J Am Vet Med Assoc
. 226(4):575-9. 2005

Cardiac HSA risk associated with spay/neuter (Cardiac tumors in dogs: 1982-1995). Ware WA, Hopper DL.
J Vet Intern Med
. 1999 Mar-Apr;13(2):95-103.

Hemangiosarcoma: Skin, Subcutaneous and Intramuscular

Cutaneous hemangiosarcoma in 25 dogs: A retrospective study. Ward J, Fox LE, Calderwood-Mays MB, et al.
J Vet Intern Med
8:345-48, 1994

A retrospective study of visceral and nonvisceral hemangiosarcoma and hemangiomas in domestic animals. Schultheiss PC.
J Vet Diagn Invest
16(6):522, 2004.

Evaluation of outcome associated with subcutaneous and intramuscular hemangiosarcoma treated with adjuvant doxorubicin in dogs: 21 cases (2001-06). Bulakowski EJ, Philibert JC, Siegel S, et al.
J Am Vet Med Assoc
233(1):122, 2008.

Effects of palliative radiation therapy for nonsplenic hemangiosarcoma in dogs. Hillers KR, Lana SE, Fuller CR, et al.
J Am Anim Hosp Assoc
43(4):187, 2007

Herbicides, Pesticides, and Other Chemicals

Herbicide exposure and the risk of transitional cell carcinoma of the urinary bladder in Scottish Terriers. Glickman LT, et al.
J Am Vet Med Assoc
. 2004 Apr 15;224(8):1290-7.

Topical flea and tick pesticides and the risk of transitional cell carcinoma of the urinary bladder in Scottish Terriers. Raghavan M, et al.
J Am Vet Med Assoc
. 2004 Aug 1;225(3):389-94.

Epidemiologic study of insecticide exposures, obesity, and risk of bladder cancer in household dogs. Glickman LT, et al.
J Toxicol Environ Health
. 1989;28(4):407-14.

Canine exposure to herbicide-treated lawns and urinary excretion of 2,4-dichlorophenoxyacetic acid. Reynolds PM, et al.
Cancer Epidemiol Biomarkers Prev
. 1994 Apr-May;3(3):233-7.

On the association between canine malignant lymphoma and opportunity for exposure to 2,4-dichlorophenoxyacetic acid. Hayes HM, Tarone RE, Cantor KP.
Environ Res
. 1995 Aug;70(2):119-25.

Re-analysis of 2,4-D use and the occurrence of canine malignant lymphoma. Kaneene JB, Miller R.
Vet Hum Toxicol.
1999 Jun;41(3):164-70.

Case-control study of canine malignant lymphoma: positive association with dog owner’s use of 2,4-dichlorophenoxyacetic acid herbicides. Hayes HM, et al
. J Natl Cancer Inst
. 1991 Sep 4;83(17):1226-31.

Bladder cancer in pet dogs: a sentinel for environmental cancer? Hayes HM Jr, Hoover R, Tarone RE.
Am J Epidemiol
. 1981 Aug;114(2):229-33.

Disinfection byproducts and bladder cancer: a pooled analysis. Villanueva CM, et al.
Epidemiology
. 2004 May;15(3):357-67.