Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (907 page)

   Extreme leukocytosis

   Drugs (quinine, salicylates, high steroid levels, drugs that cause high glucose levels)

ESTRADIOL, UNCONJUGATED

   Definition

   Most active of endogenous estrogens, primarily produced in ovaries with additional amounts produced by adrenal glands and testes (in men).

   Other names: estradiol 17 beta, E
₂
.

   
Normal range:
see Table 16.29.

TABLE 16–29. Normal Range of Values for Estradiol, Unconjugated

   Use

   Of value, together with gonadotropins, in evaluating menstrual and fertility problems in women

   In the evaluation of gynecomastia or feminization states due to estrogen-producing tumors, menstrual cycle irregularities, and sexual maturity in female patients and in monitoring of human menopausal gonadotropin (Pergonal) therapy

   Interpretation

Increased In

   Feminization in children

   Estrogen-producing tumors