ESSENTIAL WORKUP
ED workup includes obtaining an accurate history and physical exam, stabilizing the patient and injured part, and consultation or transfer if replantation is an option.
DIAGNOSIS TESTS & NTERPRETATION
Lab
Preoperative lab studies, cultures from wounded area
Imaging
Radiographs of both amputated part and stump are important, but should not delay transport.
Diagnostic Procedures/Surgery
Determined by surgical consultant for replantation
DIFFERENTIAL DIAGNOSIS
- Involves neurologic, vascular, and soft tissue integrity and potential for replantation/revascularization
- Do not miss other major injuries with concurrent trauma.
TREATMENT
PRE HOSPITAL
- Collect all amputated body parts, including pieces of bone, tissue, and skin.
- See “Initial Stabilization” for care of amputated parts during transport.
- Transport patient and body parts to the nearest microvascular replantation center unless other major injuries require transport to the nearest trauma center:
- Air transport from remote locations should be considered if ischemia time is of concern.
INITIAL STABILIZATION/THERAPY
- Consult surgical specialist as early as possible.
- Establish IV access.
- Limit blood loss:
- Elevate injured limb.
- Direct pressure using bulky pressure dressing or pressure points if ineffective.
- Use tourniquet if above methods fail to give desired hemostasis (BP cuff 30 mm Hg > systolic BP [SBP]).
- Partial amputations bleed more because of lack of both retraction and spasm of blood vessels.
- Avoid further damage to injured part:
- Avoid vascular clamps, cautery, vessel ligation, or debridement.
- Avoid repeated exams of the stump or amputated part.
- Care of amputated part (complete and partial):
- Remove gross contamination/foreign material.
- Gently irrigate with saline (avoid antiseptics).
- Wrap in gauze moistened with saline.
- Place in clean, dry plastic bag or specimen cup.
- Place sealed bag/cup in ice water (half water, half ice) or refrigerate at 4°C.
- Never place directly onto ice or into ice water.
- Avoid dry ice to prevent freezing.
- Care of the stump:
- Irrigate with saline and cover with saline dampened gauze.
- Splint if necessary; keep partial amputations as near anatomic position as possible.
- Keep any fragments of tissue (even if seemingly insignificant) because they may be used for skin, bone, or nerve grafting
- If limb amputation, may cannulate proximal artery with 18G cannula and irrigate with tissue preservation formula, but this should be at the discretion of the surgeon
- Maintain normal blood volume with IV fluids or blood products if necessary.
ED TREATMENT/PROCEDURES
- Tetanus prophylaxis
- Adequate IV analgesia
- Patient NPO
- Prophylactic antibiotics if devitalized tissue, exposed bone, or contamination:
- Cover
Streptococcus
,
Staphylococcus aureus
, and
Clostridium perfringens
- All patients are candidates for surgical repair until a specialist deems otherwise.
- Limit ischemia time of the amputated part (i.e., early transfer if necessary).
- Patient considerations in decision to replant:
- Age
- Occupation/handedness
- Degree of motivation
- General physical condition and underlying diseases, particularly diabetes mellitus, peripheral vascular disease
- Indications for replantation (no absolute indications):
- Thumb, any level (supplies 40% of hand function)
- Multiple digits
- Hand amputations through the palm and distal wrist
- Individual digit distal to flexor digitorum superficialis tendon insertion and proximal to distal interphalangeal joint (DIP)
- Some single-digit ring avulsion injuries
- Arm proximal to midforearm (if sharp or moderately avulsed)
- Virtually all pediatric amputations (younger patients have lower success rates but better functional outcomes)
- Contraindications to replantation:
- Severely crushed or mangled parts
- Injuries at multiple levels
- Psychotic patients who willfully self-amputated the part
- Single-digit amputations proximal to the flexor digitorum superficialis muscle insertion
- Amputated parts with tendons avulsed from musculotendinous junctions
- Lower extremities rarely attempted and usually in children
- Unstable patients secondary to other serious injuries or diseases
- Older patients or those with contraindications to general anesthesia
- Inappropriately prolonged ischemia time
- Fingertip amputations: Most common type of upper extremity amputation:
- Distal to DIP joint
- Primary goals of treatment:
- Maintenance of length
- Good soft-tissue coverage
- Painless fingertip with durable and sensate skin
- Nail preservation
- Better dorsal prognosis than ventral
- No exposed phalanx:
- Irrigate with saline, apply petrolatum-soaked gauze and allow to heal by secondary intention (best result in wounds <1 cm
2
).
- Small amount of exposed phalanx:
- Shorten bone with rongeur below level of the tissue and close by primary intention or allow to heal by secondary intention.
- Any bone left exposed requires additional operative procedures and consultation.
- Replantation is an option for cosmetic reasons or for occupational consideration (e.g., musicians).
- Considered open fractures if phalanx exposed, thus antibiotics are indicated.
- Preserve nail bed and nail to optimize function and cosmesis.
- Treat subungual hematomas.
- Splint to prevent trauma to healing fingertip.
- Consultation required if significant loss of bone or soft tissue for possible graft or flap
- Nonlimb amputations (penis, ear, nose): Amputated parts should be cared for similarly as above and emergently referred to a specialist for replantation:
- Penile amputations: Most often secondary to self-mutilation and psychiatric illness
- Successful replantation unlikely beyond 24 hr of cold ischemia or 6 hr of warm ischemia
- Ear amputations: Should be considered for replantation by appropriate specialist
- Nose amputations: Replantation has been successfully performed with variable results.
Pediatric Considerations
- All pediatric amputations considered for replantation
- Fingertip amputations often left to heal by secondary intention:
- Spontaneous regeneration of fingertip occurs in children even with volar fingertip amputations.
- Pediatric fingertip amputations distal to the lunula of the fingernail can be successfully replanted (unlike adults).
Geriatric Considerations
Advanced age not an absolute contraindication to replantation; however, underlying medical problems often make older patients poor surgical candidates.
MEDICATION
- First Line: Cefazolin: 0.5–1.5 g IV or IM q6–q8h (peds: 25–100 mg/kg/d divided q8h, max. 6 g/d)
- Second Line: Vancomycin 15–20 mg/kg IV q12h
- If concerned about clostridia, consider using Piperacilin/Tazobactam 80 mg/kg IV q8h
FOLLOW-UP
DISPOSITION
Admission Criteria
Hospitalization is required for all patients undergoing replantation or revascularization.
Discharge Criteria
- Mild fingertip amputations or mild degloving injuries with adequate repair and stable vasculature
- Close surgical or orthopedic follow-up is required.
Issues for Referral
- Know exact mechanism and time of injury
- Refer as early as possible
- Transfer imaging and amputated parts with patient, stored in appropriate medium
FOLLOW-UP RECOMMENDATIONS
Patients discharged but with significant skin loss should be considered for skin grafting and have close surgical follow-up.
PEARLS AND PITFALLS
- Every effort should be made to minimize ischemia time
- Expeditious consultation or transfer to appropriate surgeon and team is paramount.
- Avoid any direct contact of the amputated part with ice
- Perform thorough ATLS survey to avoid missing other less obvious, but potentially life threatening, injuries
ADDITIONAL READING
- Davis S, Chung KC. Replantation of finger avulsion injuries: a systematic review of survival and functional outcomes.
J Hand Surg
. 2011;36(4):686–694.
- Lloyd MS, Teo TC, Pickford MA, et al. Preoperative management of the amputated limb.
Emerg Med J.
2005;22(7):478–480.
- Lyn ET, Mailhot T. Hand, Runyon M. The Genitourinary System; Mckay M, Mayersak R, Facial Trauma. In: Marx J, Hockberger RS, Walls RM, et al., eds.
Rosen’s Emergency Medicine: Concepts and Clinical Practice
, 7th ed. Philadelphia, PA: Mosby/Elsevier; 2010.
- Maricevich M, Carlsen B, Mardini S, et al. Upper extremity and digital replantation.
Hand
. 2011;6:356–363.
- Sebastin SJ, Chung KC. A systematic review of the outcomes of replantation of distal digital amputation.
Plast Reconstr Surg
. 2011;128(3):723–737.
CODES
ICD9
- 885.0 Traumatic amputation of thumb (complete)(partial), without mention of complication
- 886.0 Traumatic amputation of other finger(s) (complete) (partial), without mention of complication
- 887.4 Traumatic amputation of arm and hand (complete) (partial), unilateral, level not specified, without mention of complication